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Whats infigratinib?
Infigratinib is one of the promising fgfr inhibitors, it increases height the same way as erda. It targets fibroblast growth factor receptors (fgfr) and is used in the treatment of conditions like achondroplasia and hypochondroplasia. While its mostly used to treat dwarfism, it can also be used on regular people and will behave the same way.
(related to studies done by NEJM and shows how the studies were roughly like, this image was just created by a
different group.)
In studies done by NEJM, children with achondroplasia who were given infigratinib grew taller on average compare to untreated children. This was a Huge accomplishment since it had extremely low side affects compared to similar fgfr inhibitors. Infigratinibs low risk high reward makes it a popular which potential of becoming greater.
Whats erdafitinib?
Erdafitinib, better known as erda, is a advanced bladder cancer treatment that targest fgfr, this is useful since the specific cancer increases in size due to said fgfr. Since its a drug that targets the fgfr, an obvious side affect will be an increase in height. A feature that erda has that most fgfr have to some degree (but not as common) is its concentration in urine. This is a good sign since It shows that the drug is actually working and going to your bladder.
(i wanted to point this out since it can show that your erda is actually working and is sucessfully working)
After a week of using, you can see a clear difference, youll notice a height increase from 1 cm - 2 cm. Like most other fgfr inhibators, its best to use this in your teenage years. One thing I will say about erda is that while it has a good height increase, its has high risk sorta like in a high risk high reward situation that ill get into later. While I personally wouldnt recommend erda, it is still a drug worth your while if its your last resort.
But dear, how are they similar?
Both drugs are similar since they increase height and can help with advanced bladder cancer and growth deficits. Since they both target your fgfr in a pretty similar way, you can see similar results with them. They are both overall similar drugs (in increasing height) but can be used for different reason and aren't just strictly for height.
and how are they different?
They are different in the sense of how they affect your body, their risk, and the way they are currently being studied for. Erda has a significantly higher risk of things like kidney failure, eye poisoning, and hair loss. On the other hand, infigratinib has lower risk, and is still being studied, refined, and fixed in order to make the height increase its main priority.
So dear, Which is better?
It all depends on what you are planning to use it for. If you have bladder cancer, erda is the obvious choice, but if you want an increase in height use infi. While both of these drugs are excellent for an increase in height, i'll personally have to go with infigratinib since its low risk high reward.
Conclusion?
In conclusion, infigratinib is still being worked on but it currently seems like the best choice for extremely obvious reason. Both drugs exceed in there own respective field but infi is the best for overall growth and safety.
(ps, this is NOT the thread i am talking about, i want contributor so i will keep making high effort posts)
Whats infigratinib?
Infigratinib is one of the promising fgfr inhibitors, it increases height the same way as erda. It targets fibroblast growth factor receptors (fgfr) and is used in the treatment of conditions like achondroplasia and hypochondroplasia. While its mostly used to treat dwarfism, it can also be used on regular people and will behave the same way.
(related to studies done by NEJM and shows how the studies were roughly like, this image was just created by a
different group.)
In studies done by NEJM, children with achondroplasia who were given infigratinib grew taller on average compare to untreated children. This was a Huge accomplishment since it had extremely low side affects compared to similar fgfr inhibitors. Infigratinibs low risk high reward makes it a popular which potential of becoming greater.
Whats erdafitinib?
Erdafitinib, better known as erda, is a advanced bladder cancer treatment that targest fgfr, this is useful since the specific cancer increases in size due to said fgfr. Since its a drug that targets the fgfr, an obvious side affect will be an increase in height. A feature that erda has that most fgfr have to some degree (but not as common) is its concentration in urine. This is a good sign since It shows that the drug is actually working and going to your bladder.
(i wanted to point this out since it can show that your erda is actually working and is sucessfully working)
After a week of using, you can see a clear difference, youll notice a height increase from 1 cm - 2 cm. Like most other fgfr inhibators, its best to use this in your teenage years. One thing I will say about erda is that while it has a good height increase, its has high risk sorta like in a high risk high reward situation that ill get into later. While I personally wouldnt recommend erda, it is still a drug worth your while if its your last resort.
But dear, how are they similar?
Both drugs are similar since they increase height and can help with advanced bladder cancer and growth deficits. Since they both target your fgfr in a pretty similar way, you can see similar results with them. They are both overall similar drugs (in increasing height) but can be used for different reason and aren't just strictly for height.
and how are they different?
They are different in the sense of how they affect your body, their risk, and the way they are currently being studied for. Erda has a significantly higher risk of things like kidney failure, eye poisoning, and hair loss. On the other hand, infigratinib has lower risk, and is still being studied, refined, and fixed in order to make the height increase its main priority.
So dear, Which is better?
It all depends on what you are planning to use it for. If you have bladder cancer, erda is the obvious choice, but if you want an increase in height use infi. While both of these drugs are excellent for an increase in height, i'll personally have to go with infigratinib since its low risk high reward.
Conclusion?
In conclusion, infigratinib is still being worked on but it currently seems like the best choice for extremely obvious reason. Both drugs exceed in there own respective field but infi is the best for overall growth and safety.
(ps, this is NOT the thread i am talking about, i want contributor so i will keep making high effort posts)
Oral Infigratinib Improves Growth in Children with Achondroplasia, finds study
Researchers have identified in a new study that oral infigratinib, an FGFR1-3 selective tyrosine kinase inhibitor, improves annualized height velocity in children with achondroplasia....
Infigratinib Oral Capsules
my.clevelandclinic.org
Erdafitinib: MedlinePlus Drug Information
Erdafitinib: learn about side effects, dosage, special precautions, and more on MedlinePlus
FDA approves erdafitinib for urothelial carcinoma
On January 19, 2024, the Food and Drug Administration approved erdafitinib (Balversa, Janssen Biotech) for locally advanced or metastatic urothelial carcinoma.
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