I have been macrodosing vitamin A (retinal palmynate) for 3 weeks now. Just got bloodwork done and my doc said my liver should be ok as long as I keep up glutathione. I have noticed a slight accutane-like effect on my skin texture. I have been taking 20,000 IUs per day (2x upper intake for adult men). Am at 6'1, 175 lbs currently and 20.8 BMI.