does anyone know

[pompompurino]

if there’s any links between glp-1s and mental health? tbh i genuinely feel like when i started taking it my mental health declineddd

i started taking it in april which is when my mental got gigafucked, like i’ve never had this shit of depression in my goddamn life

tagging ppl who might know:
@slopslinger @Schizotypalcel @BlendedBlade
@Randomized Shame

 

[BlendedBlade🧿]

The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy - Scientific Reports

This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity...

www.nature.com

 

[pompompurino]

the last time i dealt with any depression was in like 2021, but that was bc we were in quarantine and we got no sun, etc also had an eating disorder in that time period

 

[pompompurino]

The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy - Scientific Reports

This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity...

www.nature.com

tysm

 

[Schizotypalcel]

Just think about how the physical symptoms are effecting you, that should say it all.

 

[TonyDr]

if there’s any links between glp-1s and mental health? tbh i genuinely feel like when i started taking it my mental health declineddd

i started taking it in april which is when my mental got gigafucked, like i’ve never had this shit of depression in my goddamn life

tagging ppl who might know:
@slopslinger @Schizotypalcel @BlendedBlade
@Randomized Shame

The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy - Scientific Reports

This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity...

www.nature.com

Also i suspect a total nuke of the intestines microbiota, who can also explain mental health decline, since it is connected. Do you have issues to..yk... toilet correctly ?

 

[pompompurino]

The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy - Scientific Reports

This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity...

www.nature.com

damn… just read the abstract, 195% higher risk of developing major depression

 

[Grilldaddy83]

Stop harming your body by taking unnatural substances

 

[NewFuckingDay]

Stop harming your body by taking unnatural substances

Harming your body with glp 1s

 

[pompompurino]

The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy - Scientific Reports

This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity...

www.nature.com

Also i suspect a total nuke of the intestines microbiota, who can also explain mental health decline, since it is connected. Do you have issues to..yk... toilet correctly ?

i have no issues w the toilet tbh, but the intestinal microbiota definitely gets fucked.
the most i feel/get is nausea, sulfur burps, painful belly aches when i eat ‘too much’
legit got a horrible bellyache yesterday bc i ate two bites of a sandwich lol

 

[NewFuckingDay]

less appetite = less candy and ice cream = sadness

 

[Grilldaddy83]

Harming your body with glp 1s

View attachment 150360

They literally got depression from it dude

 

[swanneo]

it seems like it has been a cause for concern although not listed as one of the main side effects. it can be a combination of factors but if you're feeling depressed lately stop taking it for a while, you're at a good weight and if u want to lose u can do it without it!

In Silico Pharmacogenomic Assessment of Glucagon-like Peptide-1 (GLP1) Agonists and the Genetic Addiction Risk Score (GARS) Related Pathways: Implications for Suicidal Ideation and Substance Use Disorder

Introduction: Glucagon-Like Peptide-1 Receptor (GLP1R) agonists have become widespread anti-obesity/diabetes pharmaceuticals in the United States. Aim: This article aimed to provide our current knowledge on the plausible mechanisms linked to the role of Ozempic (Semaglutide), which is...

doi.org

 

[NewFuckingDay]

They literally got depression from it dude

A shooting star flew past me and I stepped on a snail at the same time I guess shooting stars are the causation of snails being stampeded

 

[Grilldaddy83]

A shooting star flew past me and I stepped on a snail at the same time I guess shooting stars are the causation of snails being stampeded

Dnr

 

[prettybird]

if there’s any links between glp-1s and mental health? tbh i genuinely feel like when i started taking it my mental health declineddd

i started taking it in april which is when my mental got gigafucked, like i’ve never had this shit of depression in my goddamn life

tagging ppl who might know:
@slopslinger @Schizotypalcel @BlendedBlade
@Randomized Shame

this is actually a really good question let me see if i can find anything because im very interested

 

[pompompurino]

less appetite = less candy and ice cream = sadness

i would say this is right but glp-1 targets the hypothalamus which controls hunger and satiety but also mood regulation
effects the hippocampus too, has glp-1 receptors but it also deals w emotional regulation
also, amygdala, reward pathways, etc.
honestly i should’ve done more research on this rather than the physical side effects.

 

[TonyDr]

i have no issues w the toilet tbh, but the intestinal microbiota definitely gets fucked.
the most i feel/get is nausea, sulfur burps, painful belly aches when i eat ‘too much’
legit got a horrible bellyache yesterday bc i ate two bites of a sandwich lol

Idk how is it called in english, gut microbiome also i think

But anyways it's complicated because glp-1 can improves the growth of some good bacterias BUT will nuke the hormonal production. Because yes intestines will produce multiple hormones who will be delivered into the bloodstream, and it's connected to the brain. Lack of these hormones = depression risks

 

[pompompurino]

They literally got depression from it dude

i wouldn’t blame it all on the sema or any glp-1, no

 

[hardcapped]

if there’s any links between glp-1s and mental health? tbh i genuinely feel like when i started taking it my mental health declineddd

i started taking it in april which is when my mental got gigafucked, like i’ve never had this shit of depression in my goddamn life

tagging ppl who might know:
@slopslinger @Schizotypalcel @BlendedBlade
@Randomized Shame

maybe because your not eating enough

 

[pompompurino]

i wouldn’t blame it all on the sema or any glp-1, no

like im sure it caused me to feel muchhhh worse, but i definitely had at least some form of anxiety or something