Guide Finasteride

[𝔓𝔬𝔩𝔶𝔪𝔬𝔯𝔭𝔥𝔦𝔰𝔪]

Finasteride

Finasteride inhibits type II 5-α-reductase, lowering scalp DHT and slowing miniaturization in androgenetic alopecia. Consistent use preserves density and increases hair counts in controlled trials. Effects stabilize after ~6–12 months and are maintained with continued use. It is pharmacologic, not “natural,” and remains a cornerstone when the goal is long-term scalp preservation.

Spoiler: Way it works

Blocks conversion of testosterone to DHT in follicular units with ~60–65% scalp DHT reduction; serum DHT typically drops ~60–70% at therapeutic dosing. Reduced DHT- decreased androgen signaling in susceptible follicles, slower miniaturization and improved anagen ratios.

Spoiler: Evidence

Randomized, placebo-controlled trials show increased hair counts and global photographic improvements at the vertex and mid-scalp. Longitudinal data confirm maintenance with ongoing therapy, with relapse on discontinuation.

Spoiler: Notes / Stack

Commonly stacked with topical/oral minoxidil and ketoconazole shampoo. Consider labs/MD oversight if you have endocrine concerns. Any switch to dutasteride should consider higher DHT suppression and risk/benefit.

References

https://pubmed.ncbi.nlm.nih.gov/9554768/

https://pubmed.ncbi.nlm.nih.gov/10554063/

https://pubmed.ncbi.nlm.nih.gov/15030348/

 

[RRM]

ok

 

[Tumor]

Nice guide king

 

[sigmagoy]

Mirin