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First I’ll answer the easiest question,how can it not work when people see results?
It’s a simple answer that dosent need any scientific backing. People often combine GHK-CU with other way more effective skincare compounds such as tretinoin,salicylic acid etc. the results you see are mostly from the secondary products.
Why would GHK-CU never/barely work?
The skins stratum corneum acts as a protective shield,meaning if inject it less than than a margin (1%-0.5%) will pass through it even with good liposomal carriers [Journal of Investigative Dermatogoly,2022). The skin barrier is designed to block large peptide molecules. Lab studies also use a concentration of up to 10% meanwhile the GHK-CU most likely buy has a concentration of less 0.01,yes most sources!
GHK-CU modulates collagen degrading enzymes and dosen’t promote collagen synthesis. If you apply it topically it would still be useless,the copper peptide will not reach the fibroblasts in the dermis,injecting it dermally won’t also help due to the fact that utilization is poor. If you’re not deficient in copper your body has enough copper for multiple skin processes including collagen synthesis.
Another and the final important reason why it’s cope is due to the fact that even if it manages to utilize your skin will quickly get densensitized to it.
Do your own research on how copper ions work,hopefully this is useful.
It’s a simple answer that dosent need any scientific backing. People often combine GHK-CU with other way more effective skincare compounds such as tretinoin,salicylic acid etc. the results you see are mostly from the secondary products.
Why would GHK-CU never/barely work?
The skins stratum corneum acts as a protective shield,meaning if inject it less than than a margin (1%-0.5%) will pass through it even with good liposomal carriers [Journal of Investigative Dermatogoly,2022). The skin barrier is designed to block large peptide molecules. Lab studies also use a concentration of up to 10% meanwhile the GHK-CU most likely buy has a concentration of less 0.01,yes most sources!
GHK-CU modulates collagen degrading enzymes and dosen’t promote collagen synthesis. If you apply it topically it would still be useless,the copper peptide will not reach the fibroblasts in the dermis,injecting it dermally won’t also help due to the fact that utilization is poor. If you’re not deficient in copper your body has enough copper for multiple skin processes including collagen synthesis.
Another and the final important reason why it’s cope is due to the fact that even if it manages to utilize your skin will quickly get densensitized to it.
Do your own research on how copper ions work,hopefully this is useful.