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How do androgens impact the OPG/RANKL axis
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web to complicated to explain dnrHow do androgens impact the OPG/RANKL axis
WhySupresses osteoclast
The uhHow do androgens impact the OPG/RANKL axis
decreases OPG/RANKL ratio overall which suppresses osteoclast
why does this happen thoughdecreases OPG/RANKL ratio overall which suppresses osteoclast
Because it fucking doeswhy does this happen though
whats the exact process that makes them suppress the osteoclastBecause it fucking does
way too lazy to explain sorry bubsHow do androgens impact the OPG/RANKL axis
just say you dkway too lazy to explain sorry bubs
I actually do know I just dont want to explainjust say you dk
sure bubI actually do know I just dont want to explain
They bind onto osteoclast which suppresses itwhats the exact process that makes them suppress the osteoclast
what ever lets u sleep at night babysure bub
Oh is it maybe because of enhanced wnt activity which then causes wnt/trf/LEC/tnfrsf11b gene transcription to produce more OPG thus skewing the ratio in favor of formation?decreases OPG/RANKL ratio overall which suppresses osteoclast
what makes them bind thoThey bind onto osteoclast which suppresses it
I don’t fucking knowOh is it maybe because of enhanced wnt activity which then causes wnt/trf/LEC/tnfrsf11b gene transcription to produce more OPG thus skewing the ratio in favor of formation?
okay daddy pls mark solution btwincrease opg and reduce rankl activity, which means less rank activation and less osteoclast formation. Basically, they help reduce bone breakdown and support bone density. Testosterone can also convert into estrogen, which further affects the opg/rankl pathway.