EndlessRequiem
Active member
- Joined
- Feb 16, 2025
- Messages
- 138
- Reputation
- 242
Vitamin C has shown to significantly increase the rate of change in orthodontics by enabling osteogenesis.
In an experiment performed on rats the tooth movement increased by at least 20% (3.61 case vs 2.96 control, they don't mention if there is already a distance beforehand.)
Osteoclast counts where almost 40% higher in the case group (onf 0.036p though since the standard dev was high).
www.ncbi.nlm.nih.gov
Some of the references are also worth nothing.
It seems high vit c might induced copper definiancy could undo the positive effect so taking enough copper would probably be a good idea, especially if one is already supplementing zinc.
Also remember that Vitamin K induces osteoclast apoptosis. Since you actually want to change bone this doesn't help you much for moving teeth/bone and taking a lot of vit C should counteract the effect.
On a side note (since you're now running osteogenesis game anyway):
Permajutting (with the help of some device, for instance a mandibular advancement device used in sleep apnea treatment) actually induces remodelling of the condylars.
Again a rat study with bite-jumping devices:
www.ncbi.nlm.nih.gov
In an experiment performed on rats the tooth movement increased by at least 20% (3.61 case vs 2.96 control, they don't mention if there is already a distance beforehand.)
Osteoclast counts where almost 40% higher in the case group (onf 0.036p though since the standard dev was high).
Effect of Dietary Vitamin C on Orthodontic Tooth Movement in Rats - PMC
Bone remodeling occurs during orthodontic treatment; this process enables tooth movement. Many factors can affect bone remodeling at the cellular level, such as nutritional supplements that can affect tooth movement. The present study was designed ...

Some of the references are also worth nothing.
It seems high vit c might induced copper definiancy could undo the positive effect so taking enough copper would probably be a good idea, especially if one is already supplementing zinc.
Also remember that Vitamin K induces osteoclast apoptosis. Since you actually want to change bone this doesn't help you much for moving teeth/bone and taking a lot of vit C should counteract the effect.
On a side note (since you're now running osteogenesis game anyway):
Permajutting (with the help of some device, for instance a mandibular advancement device used in sleep apnea treatment) actually induces remodelling of the condylars.
Again a rat study with bite-jumping devices:

Forward mandibular positioning enhances condylar adaptation in adult rats - PubMed
The aim of this investigation was to assess quantitatively the adaptive changes in the condyles of adult rats to forward mandibular positioning. The level of types II and X collagen expressed in the condyles of adult rats was compared with that formed in response to forward mandibular...
