WhitePussyEater
Owner of all Jerusalem-based Pussy
- Joined
- Dec 24, 2025
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What is Retatrutide?
Retatrutide is a peptide medication that consists of 39 linked amino acids. It’s the first incretin-based peptide to target 3 different receptors. These 3 receptors are the glucagon receptors, the GLP-1 receptor, and the GIP receptor. As reta has gained more popularity on social media apps such as tiktok, insta, etc; the usage of other weight loss peptides such as terzapatide and semaglutide has gone down. With a number of phase III trials on reta, coming to a close in early and mid 2026, we’ll likely see reta be FDA-approved by late 2026, with all safety concerns being acknowledged for.
Benefits to Pinning Retatrutide
• Improves blood glycemic control
• Increases the possibility of lipolysis being used in the metabolic state
• Increases insulin sensitivity
• Suppresses appetite by mimicking the three receptors listed (GLP-1, GIP, and Glucagon receptors)
• Undeniable weight loss
• Induces osteoblast activity
Side Effects/Safety Cautions
• Can cause adverse reactions in the GI tract
• Can increase the risk of hypoglycemia
• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Constipation
Dosage
Since reta has a half life of 6-7 days (the time it takes for more than half of the concentration of the substance to be exterminated from the body), it’s meant to be injected weekly. The highest tested dosages range from 8-12 mg, with 12 mg delivering the most results, with the individual losing 24% of their body weight in 48 weeks if I’m not mistaken. You increase the risk of developing GI issues and metabolism issues when beginning your cycle at a high amount. For the first 1-4 weeks of your reta treatment, I’d say 2-4 mg is recommended. Each 4 weeks, you can adjust by about 2 mg, or limit this amount based off the symptoms you may have.
Rather low effot post, just had this in the vault. Post on insulin sensitivity/resistance coming next
Retatrutide is a peptide medication that consists of 39 linked amino acids. It’s the first incretin-based peptide to target 3 different receptors. These 3 receptors are the glucagon receptors, the GLP-1 receptor, and the GIP receptor. As reta has gained more popularity on social media apps such as tiktok, insta, etc; the usage of other weight loss peptides such as terzapatide and semaglutide has gone down. With a number of phase III trials on reta, coming to a close in early and mid 2026, we’ll likely see reta be FDA-approved by late 2026, with all safety concerns being acknowledged for.
Benefits to Pinning Retatrutide
• Improves blood glycemic control
• Increases the possibility of lipolysis being used in the metabolic state
• Increases insulin sensitivity
• Suppresses appetite by mimicking the three receptors listed (GLP-1, GIP, and Glucagon receptors)
• Undeniable weight loss
• Induces osteoblast activity
Side Effects/Safety Cautions
• Can cause adverse reactions in the GI tract
• Can increase the risk of hypoglycemia
• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Constipation
Dosage
Since reta has a half life of 6-7 days (the time it takes for more than half of the concentration of the substance to be exterminated from the body), it’s meant to be injected weekly. The highest tested dosages range from 8-12 mg, with 12 mg delivering the most results, with the individual losing 24% of their body weight in 48 weeks if I’m not mistaken. You increase the risk of developing GI issues and metabolism issues when beginning your cycle at a high amount. For the first 1-4 weeks of your reta treatment, I’d say 2-4 mg is recommended. Each 4 weeks, you can adjust by about 2 mg, or limit this amount based off the symptoms you may have.
Rather low effot post, just had this in the vault. Post on insulin sensitivity/resistance coming next
