Guide Diuretics 101 - Definition, Use and Risks

[ThrowingAway]

Introduction

>Diuretics increase urine production, while they also promote water and electrolyte excretion.

>Common uses:
>

Spoiler: medical

medical (hypertension, edema, heart/kidney issues)

> BUT

Spoiler: aesthetics

they also promote extracellular water loss, basically removing that excess from the sodium retention

Function / Types

> Diuretics act on the kidneys on different segments of the

Spoiler: nephron

( the neuron of kidneys)

trough the Loop of Henle/ Distal convoluted tubule/ Collecting duct

> basically inhibits ion reabsorption

> different mechanisms -
> for instance furosemide, secreted from the tubule, blocks Na, K and Cl in the loop of henle - STRONG

> thiazide inhibits Na and Cl in the distal convoluted tubule - moderate

> "natural" through caffeine and green tea - strength varies from the dose

Risks / Side Effects

> Electrolyte disbalance - not only water and sodium get excreted but also other electrolytes like K, Mg .......

> This could lead to cramps, energy loss, muscle hypotension, dizziness, dehydration, kidney strain, arythmia.....



My Advice

Caffeine for normal day to day - other cognitive boosts and wtv , cycle one week off one month on, It has a 7 hours half life so be wary of sleep. I suggest taking it at 10am at latest. 400mg a day with 3L of water

Furosemide for very important social gaatherings, use with caution

enjoy

 

[AClonedTyrone]

I feel as though most of this is common knowledge, also diuretics will just cause you to retain more water once the effect has worn off. You can also permanently effect the way your body naturally debloats and flushes excess fluids. I’ve already gone over that in my bloat cope thread. Mirin effort through.

 

[ThrowingAway]

I feel as though most of this is common knowledge, also diuretics will just cause you to retain more water once the effect has worn off.

Yeah bro lets just blast furosemide like retards and expect the body to not compensate for it

 

[ThrowingAway]

I feel as though most of this is common knowledge, also diuretics will just cause you to retain more water once the effect has worn off. You can also permanently effect the way your body naturally debloats and flushes excess fluids. I’ve already gone over that in my bloat cope thread. Mirin effort through.

You would be suprised by how many people dont actually know, wdym by permanently naturally debloating

 

[AClonedTyrone]

Yeah bro lets just blast furosemide like retards and expect the body to not compensate for it

I don’t understand your hostile view point, I’m simply stating that this is rather common knowledge in the community and that more often than not people can go overboard with it. Calm down n***a

 

[AClonedTyrone]

You would be suprised by how many people dont actually know, wdym by permanently naturally debloating

The concept of “debloat” is cope and a lie there is no perms bloat that’s just water retention of which the body has its own system to deal with and flush out, a good diet will do more for you long term the furosemide will for a few hours. I have an in-depth thread on this. There is no “debloat” as there is no “perma bloat”

 

[ThrowingAway]

I don’t understand your hostile view point, I’m simply stating that this is rather common knowledge in the community and that more often than not people can go overboard with it. Calm down n***a

n***a im chilled out lmao

On .org maybe, here no and i rarely see it being mentioned

 

[syrian_lily141]

Introduction

>Diuretics increase urine production, while they also promote water and electrolyte excretion.

>Common uses:
>

Spoiler: medical

medical (hypertension, edema, heart/kidney issues)

> BUT

Spoiler: aesthetics

they also promote extracellular water loss, basically removing that excess from the sodium retention

Function / Types

> Diuretics act on the kidneys on different segments of the

Spoiler: nephron

( the neuron of kidneys)

trough the Loop of Henle/ Distal convoluted tubule/ Collecting duct

> basically inhibits ion reabsorption

> different mechanisms -
> for instance furosemide, secreted from the tubule, blocks Na, K and Cl in the loop of henle - STRONG
View attachment 266791
> thiazide inhibits Na and Cl in the distal convoluted tubule - moderate
View attachment 266787

> "natural" through caffeine and green tea - strength varies from the dose
View attachment 266795


Risks / Side Effects

> Electrolyte disbalance - not only water and sodium get excreted but also other electrolytes like K, Mg .......

> This could lead to cramps, energy loss, muscle hypotension, dizziness, dehydration, kidney strain, arythmia.....



My Advice

Caffeine for normal day to day - other cognitive boosts and wtv , cycle one week off one month on, It has a 7 hours half life so be wary of sleep. I suggest taking it at 10am at latest. 400mg a day with 3L of water

Furosemide for very important social gaatherings, use with caution

enjoy

gang just pee wtf

 

[ThrowingAway]

gang just pee wtf

Dawg.... just say DNR

 

[Pearex]

I appreciate your efforts, especially your avoidance of encouraging the indiscriminate use of these substances. But honestly, there are some technical errors in this guide that need correcting and could pose a life threatening risk

 

[ThrowingAway]

I appreciate your efforts, especially your avoidance of encouraging the indiscriminate use of these substances. But honestly, there are some technical errors in this guide that need correcting and could pose a life threatening risk

Well, share so i fix them, will appreciate

 

[AClonedTyrone]

n***a im chilled out lmao

On .org maybe, here no and i rarely see it being mentioned

Because most people here have already been through and left org. This had an entirely different feel to it as a com. The people here are already aware of most of what’s common knowledge on org and thus it needs less coverage. I appreciate your work but this guide is as useful as a google search because it’s topical.

 

[Pearex]

Well, share so i fix them, will appreciate

for instance furosemide, secreted from the tubule, blocks Na, K and Cl in the loop of henle - STRONG

> thiazide inhibits Na and Cl in the distal convoluted tubule - moderate

Although thiazides appear to have a weaker effect, they have a much longer half life. While furosemide is quickly eliminated from the body, the effects of thiazides last throughout the day, and the risk of disrupting electrolyte balance in the long term is more insidious. Furthermore, the significant side effects of thiazides, such as raising blood sugar and uric acid levels (risking diabetes and gout) have not been mentioned at all

natural" through caffeine and green tea - strength varies from the dose

Caffeine and green tea are not technically classified as diuretic drugs. They are substances that accelerate metabolism and increase renal blood flow. In someone who regularly consumes caffeine, the body develops tolerance to this effect, and after a while, the diuretic effect almost disappears. Drugs do not have such a tolerance mechanism they drain the body every time

This could lead to cramps, energy loss, muscle hypotension, dizziness, dehydration, kidney strain, arythmia.....

The kidney is not a muscle group. Diuretics do not stress the kidney they chemically manipulate kidney function (ion transport)

The images you uploaded clearly show the loss of K+, the loss of hydrogen, and the change in Ca2+
the guide focuses solely on na and water loss. However, these medications directly alter bone health (calcium retention/excretion) and the body's pH balance

My Advice

Caffeine for normal day to day - other cognitive boosts and wtv , cycle one week off one month on, It has a 7 hours half life so be wary of sleep. I suggest taking it at 10am at latest. 400mg a day with 3L of water

Drinking excessive water while taking diuretics further disrupts sodium balance, increasing the risk of hyponatremia. This can lead to cerebral edema, confusion, and fainting. Trying to replace what the medication is expelling goes against the mechanism

Recommending 400 mg of caffeine a day and then saying pay attention to your sleep is physiologically impossible. Due to caffeine's half life, even this amount taken at 10 am will prevent the transition to deep sleep at night. In a system without quality sleep, cognitive enhancement cannot occur

 

[HeavyMetalGoth]

just drink alc for diuretics but not too much

 

[Pearex]

just drink alc for diuretics but not too much

Drinking alcohol to increase urination is similar to trying to quench your thirst by drinking seawater

 

[HeavyMetalGoth]

Drinking alcohol to increase urination is similar to trying to quench your thirst by drinking seawater

not just for urination also to clear out your stomach
seawater has salt in it and doesnt get you drunk either

 

[Pearex]

not just for urination also to clear out your stomach
seawater has salt in it and doesnt get you drunk either

Alcohol doesn't cleanse the stomach it irritates the stomach lining, causing gastritis or ulcers. If you're referring to vomiting that's not cleansing it's the body's reaction to intoxication

 

[ThrowingAway]

Although thiazides appear to have a weaker effect, they have a much longer half life. While furosemide is quickly eliminated from the body, the effects of thiazides last throughout the day, and the risk of disrupting electrolyte balance in the long term is more insidious. Furthermore, the significant side effects of thiazides, such as raising blood sugar and uric acid levels (risking diabetes and gout) have not been mentioned at all



Caffeine and green tea are not technically classified as diuretic drugs. They are substances that accelerate metabolism and increase renal blood flow. In someone who regularly consumes caffeine, the body develops tolerance to this effect, and after a while, the diuretic effect almost disappears. Drugs do not have such a tolerance mechanism they drain the body every time



The kidney is not a muscle group. Diuretics do not stress the kidney they chemically manipulate kidney function (ion transport)





The images you uploaded clearly show the loss of K+, the loss of hydrogen, and the change in Ca2+
the guide focuses solely on na and water loss. However, these medications directly alter bone health (calcium retention/excretion) and the body's pH balance



Drinking excessive water while taking diuretics further disrupts sodium balance, increasing the risk of hyponatremia. This can lead to cerebral edema, confusion, and fainting. Trying to replace what the medication is expelling goes against the mechanism

Recommending 400 mg of caffeine a day and then saying pay attention to your sleep is physiologically impossible. Due to caffeine's half life, even this amount taken at 10 am will prevent the transition to deep sleep at night. In a system without quality sleep, cognitive enhancement cannot occur

From what i see, you create scenarios which i havent said or you alter them so you emd up as the victorious one

 

[Pearex]

From what i see, you create scenarios which i havent said or you alter them so you emd up as the victorious one

If you claim that the ion channel changes (ROMK NKCC2 etc) in your images do not create these risks, I would expect you to explain your mechanism