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Info Info Dump: Isotretinoin (Accutane)

genio said:
-“But saar, it’ll stunt my growth if I take it during puberty”
Studies have shown that Isotretinoin decreases HGH, IGF-1, testosterone, etc. in pubescent boys, but this will only slow your growth velocity and will not stunt your final adult height. Long bones like the ones involved in growth experience catch-up growth, so you’ll be fine.
Click to expand...
eliminating competion i see
 
genio said:
How does Isotretinoin work?
It kills sebocytes (the cells that produce sebum) which are the main cause of acne. It’s very hard to have acne without sebocytes as sebum is what clogs your pores allowing bacteria to form. It basically kills acne from its origin.
-Study

Other benefits on skin
It increases collagen production causing better skin elasticity and having a positive effect on photoaging skin.
-Study

Misconceptions about Isotretinoin
-“But saar, it has so many side effects.”
This is true at standard dosages, but can EASILY be avoided with correct dosing. Do not take large amounts of Isotretinoin within a short time frame, but rather spread it out. Cumulative dose has been shown to be one of the most important factors when taking Isotretinoin. You’ll experience the same skin benefits with minimal side effects if you take a low dose over a longer span of time. Note that you'll have a higher chance of relapse if you do get off though as compared to a high dose over a short time.
For example:
3000mg over 1 month = Clear skin, skin benefits, but a lot of side effects (most likely to not relapse if you get off)
3000mg over 6 months = Same clear skin and skin benefits, but minimal side effects (more likely to relapse if you get off)
-Study 1, Study 2, Study 3

-“But saar, it’ll stunt my growth if I take it during puberty”
Studies have shown that Isotretinoin decreases HGH, IGF-1, testosterone, etc. in pubescent boys, but this will only slow your growth velocity and will not stunt your final adult height. Long bones like the ones involved in growth experience catch-up growth, so you’ll be fine.
-Study 1, Study 2, Study 3, Study 4
Click to expand...
@TonyDr can i get contributor
 
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Day 1 of leaking gatekeep guides, best way to lose water weight.

This debloat method is so powerful even Jordan barret has admitted to using it. WHAT YOU WILL NEED: Rope/tourniquet Hydrogen peroxide Salt/baking soda X-acto knife Syringe. Enjoy This method is truly hardcore looksmaxxing, as hardcore as canthus cutting and bones smashing but beauty...
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@TonyDr
 
Majaslovenia said:
indiamart doesnt ship to europe?
Click to expand...
They probably do but eu customs are strict as shit so your order 90% getting seized
Do some research actually im not too educated on eu customs
 
good thread if I had acne
 
genio said:
How does Isotretinoin work?
It kills sebocytes (the cells that produce sebum) which are the main cause of acne. It’s very hard to have acne without sebocytes as sebum is what clogs your pores allowing bacteria to form. It basically kills acne from its origin.
-Study

Other benefits on skin
It increases collagen production causing better skin elasticity and having a positive effect on photoaging skin.
-Study

Misconceptions about Isotretinoin
-“But saar, it has so many side effects.”
This is true at standard dosages, but can EASILY be avoided with correct dosing. Do not take large amounts of Isotretinoin within a short time frame, but rather spread it out. Cumulative dose has been shown to be one of the most important factors when taking Isotretinoin. You’ll experience the same skin benefits with minimal side effects if you take a low dose over a longer span of time. Note that you'll have a higher chance of relapse if you do get off though as compared to a high dose over a short time.
For example:
3000mg over 1 month = Clear skin, skin benefits, but a lot of side effects (most likely to not relapse if you get off)
3000mg over 6 months = Same clear skin and skin benefits, but minimal side effects (more likely to relapse if you get off)
-Study 1, Study 2, Study 3

-“But saar, it’ll stunt my growth if I take it during puberty”
Studies have shown that Isotretinoin decreases HGH, IGF-1, testosterone, etc. in pubescent boys, but this will only slow your growth velocity and will not stunt your final adult height. Long bones like the ones involved in growth experience catch-up growth, so you’ll be fine.
-Study 1, Study 2, Study 3, Study 4
Click to expand...
good thread i guess
not the best but it helped me
ill bookmark for future reference
 
just copped 300 caps of isotroin on indiamart :3
 
genio said:
Decent deal i couldve got it for like $90 tbh
Also whats the difference between the 3 types anyways
Click to expand...
isotroin and tretiva are the major brands of isotret in india
so basically the accutane of india
u can also use accufine but the quality varies, some batches can be horribly degraded bc lack of quality control in jeetfactories
ppl on .org have said they got no side effects like dry lips on accufine while others said accufine worked well so its just luck
lmk if u see side effects in few weeks
 
iqmaxx said:
isotroin and tretiva are the major brands of isotret in india
so basically the accutane of india
u can also use accufine but the quality varies, some batches can be horribly degraded bc lack of quality control in jeetfactories
ppl on .org have said they got no side effects like dry lips on accufine while others said accufine worked well so its just luck
lmk if u see side effects in few weeks
Click to expand...
n****r so im fucked
 
genio said:
n****r so im fucked
Click to expand...
IMG_8868.webp

talking abt accufine btw
its summer in india rn which is not a good sign, probably would’ve been better to order during winter
it did work for a lot of ppl tho so good luck but im not taking the chance of wasting my money
 
iqmaxx said:
View attachment 341016
talking abt accufine btw
its summer in india rn which is not a good sign, probably would’ve been better to order during winter
it did work for a lot of ppl tho so good luck but im not taking the chance of wasting my money
Click to expand...
I ordered in march
 
genio said:
How does Isotretinoin work?
It kills sebocytes (the cells that produce sebum) which are the main cause of acne. It’s very hard to have acne without sebocytes as sebum is what clogs your pores allowing bacteria to form. It basically kills acne from its origin.
-Study

Other benefits on skin
It increases collagen production causing better skin elasticity and having a positive effect on photoaging skin.
-Study

Misconceptions about Isotretinoin
-“But saar, it has so many side effects.”
This is true at standard dosages, but can EASILY be avoided with correct dosing. Do not take large amounts of Isotretinoin within a short time frame, but rather spread it out. Cumulative dose has been shown to be one of the most important factors when taking Isotretinoin. You’ll experience the same skin benefits with minimal side effects if you take a low dose over a longer span of time. Note that you'll have a higher chance of relapse if you do get off though as compared to a high dose over a short time.
For example:
3000mg over 1 month = Clear skin, skin benefits, but a lot of side effects (most likely to not relapse if you get off)
3000mg over 6 months = Same clear skin and skin benefits, but minimal side effects (more likely to relapse if you get off)
-Study 1, Study 2, Study 3

-“But saar, it’ll stunt my growth if I take it during puberty”
Studies have shown that Isotretinoin decreases HGH, IGF-1, testosterone, etc. in pubescent boys, but this will only slow your growth velocity and will not stunt your final adult height. Long bones like the ones involved in growth experience catch-up growth, so you’ll be fine.
-Study 1, Study 2, Study 3, Study 4
Click to expand...
Bump
 
dnr but read the studiees now like a good boy go supply me with some
 
genio said:
How does Isotretinoin work?
It kills sebocytes (the cells that produce sebum) which are the main cause of acne. It’s very hard to have acne without sebocytes as sebum is what clogs your pores allowing bacteria to form. It basically kills acne from its origin.
-Study

Other benefits on skin
It increases collagen production causing better skin elasticity and having a positive effect on photoaging skin.
-Study

Misconceptions about Isotretinoin
-“But saar, it has so many side effects.”
This is true at standard dosages, but can EASILY be avoided with correct dosing. Do not take large amounts of Isotretinoin within a short time frame, but rather spread it out. Cumulative dose has been shown to be one of the most important factors when taking Isotretinoin. You’ll experience the same skin benefits with minimal side effects if you take a low dose over a longer span of time. Note that you'll have a higher chance of relapse if you do get off though as compared to a high dose over a short time.
For example:
3000mg over 1 month = Clear skin, skin benefits, but a lot of side effects (most likely to not relapse if you get off)
3000mg over 6 months = Same clear skin and skin benefits, but minimal side effects (more likely to relapse if you get off)
-Study 1, Study 2, Study 3

-“But saar, it’ll stunt my growth if I take it during puberty”
Studies have shown that Isotretinoin decreases HGH, IGF-1, testosterone, etc. in pubescent boys, but this will only slow your growth velocity and will not stunt your final adult height. Long bones like the ones involved in growth experience catch-up growth, so you’ll be fine.
-Study 1, Study 2, Study 3, Study 4
Click to expand...
I want to make a massive fucking thread about accutane, a massive misconception is it’s very similar to other retinoids when in fact it has a fairly unique mechanism of action and shouldn’t really be grouped in with the others
 
True Aryan Incel said:
I want to make a massive fucking thread about accutane, a massive misconception is it’s very similar to other retinoids when in fact it has a fairly unique mechanism of action and shouldn’t really be grouped in with the others
Click to expand...
Its one of the only oral retinoids too
 
kys said:
S

SOOOOO reliable and trustworthy
Click to expand...
n***a it is reliable and trustworthy with the right seller
Do you want accutane or not
 
genio said:
n***a it is reliable and trustworthy with the right seller
Do you want accutane or not
Click to expand...
n***a i found test e 250 mg vails for 2 bucks thats fucking rat piss
 
kys said:
n***a i found test e 250 mg vails for 2 bucks thats fucking rat piss
Click to expand...
n***a nobody told you to buy injectables off indiamart
Orals are fair game
 
genio said:
How does Isotretinoin work?
It kills sebocytes (the cells that produce sebum) which are the main cause of acne. It’s very hard to have acne without sebocytes as sebum is what clogs your pores allowing bacteria to form. It basically kills acne from its origin.
-Study

Other benefits on skin
It increases collagen production causing better skin elasticity and having a positive effect on photoaging skin.
-Study

Misconceptions about Isotretinoin
-“But saar, it has so many side effects.”
This is true at standard dosages, but can EASILY be avoided with correct dosing. Do not take large amounts of Isotretinoin within a short time frame, but rather spread it out. Cumulative dose has been shown to be one of the most important factors when taking Isotretinoin. You’ll experience the same skin benefits with minimal side effects if you take a low dose over a longer span of time. Note that you'll have a higher chance of relapse if you do get off though as compared to a high dose over a short time.
For example:
3000mg over 1 month = Clear skin, skin benefits, but a lot of side effects (most likely to not relapse if you get off)
3000mg over 6 months = Same clear skin and skin benefits, but minimal side effects (more likely to relapse if you get off)
-Study 1, Study 2, Study 3

-“But saar, it’ll stunt my growth if I take it during puberty”
Studies have shown that Isotretinoin decreases HGH, IGF-1, testosterone, etc. in pubescent boys, but this will only slow your growth velocity and will not stunt your final adult height. Long bones like the ones involved in growth experience catch-up growth, so you’ll be fine.
-Study 1, Study 2, Study 3, Study 4
Click to expand...
@kys not a guide but good info
 
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