ianeptine for bdnf, trkb upregulation, hippocampal and pfc dendritic spine proliferation, reverese stress induced degeneration, glutamine transporter decrease and reduction in mglur1 and mglur3 expression, g protein coupled signaling through mor to alleviate depression, ppar delta agonist (could be good for short term), insulin sensitising, CREBphosphorylation induced neurotrophic expression, increase in met-enkephalin
rasagiline for gdnf, bcl2 proteins upregulation, mao b inhibition , tyrosine hydroxilase increase, extreme anti oxidant activity in the brain through 1 amino-indan metabolite
amantadine (cycled) for tyrosine hydroxylase expression increase, aacd increase, postsynaptic dopamine receptor conformation change for more singalling, eliminating cfs through mitochondrial protection and cytoskeleton balancing, cell water balancing, nmda antagonism, nam of alpha 7 acetylcholine (the nam property alone should techincally be bad but im inclined to believe everything u/sirsadalot comes up with on his own as some holy grail is more than likely just trash like d serine, but in any case should be balanced with by alcar or tropisetron if needs be) , insulin sensitising and enhancing glucose uptake
agmatine for peroxynitrite clearance, inos decrease, enos activation, alleviating dysfunction gut brain axis, cortisol reduction
magnesium ,theanine for cortisol reduction, alpha brain waves in eeg suggesting possibly higher pfc activation and glycine for gut lining, sparing glutathione etc
alcar for upregulation of d1, could possibly work well with sulbutiamine
piracetam when needs be through ampa , bilateral hemisphere connection strengthening, increased choline uptake and blood flow,cytoprotective
creatine for increasing the cr/pcr ratio in brain and muscles for burst-fire evoked response to stimuli
I also take vitamin b12 and b9 (methylated)for light sensitising properties(purported) to fix my dspd but Im currently out of them
Aspirin for cox 2 inhibition and to resolve headaches (usually only induced by piracetam)
high dose riboflavin, coq10, niacinamide sometimes for mitochondrial protection
What I need to get:
SR9011 for mitochondrial biogenesis and CLOCK gene activation
low dose naltrexone for upregulation of opiod tone and reducing any chronic inflammation state (prone to if higher body fat)
Testosterone later this year (interested in how it affects my mental state mainly)
7 8 dhf ,impossible for me to get but would synergise well with the stack imo
other ones I would want would be gb 115, neboglamine, acd 156 , tak 653, dihexa, nsi 186, prl 583
@genio
rasagiline for gdnf, bcl2 proteins upregulation, mao b inhibition , tyrosine hydroxilase increase, extreme anti oxidant activity in the brain through 1 amino-indan metabolite
amantadine (cycled) for tyrosine hydroxylase expression increase, aacd increase, postsynaptic dopamine receptor conformation change for more singalling, eliminating cfs through mitochondrial protection and cytoskeleton balancing, cell water balancing, nmda antagonism, nam of alpha 7 acetylcholine (the nam property alone should techincally be bad but im inclined to believe everything u/sirsadalot comes up with on his own as some holy grail is more than likely just trash like d serine, but in any case should be balanced with by alcar or tropisetron if needs be) , insulin sensitising and enhancing glucose uptake
agmatine for peroxynitrite clearance, inos decrease, enos activation, alleviating dysfunction gut brain axis, cortisol reduction
magnesium ,theanine for cortisol reduction, alpha brain waves in eeg suggesting possibly higher pfc activation and glycine for gut lining, sparing glutathione etc
alcar for upregulation of d1, could possibly work well with sulbutiamine
piracetam when needs be through ampa , bilateral hemisphere connection strengthening, increased choline uptake and blood flow,cytoprotective
creatine for increasing the cr/pcr ratio in brain and muscles for burst-fire evoked response to stimuli
I also take vitamin b12 and b9 (methylated)for light sensitising properties(purported) to fix my dspd but Im currently out of them
Aspirin for cox 2 inhibition and to resolve headaches (usually only induced by piracetam)
high dose riboflavin, coq10, niacinamide sometimes for mitochondrial protection
What I need to get:
SR9011 for mitochondrial biogenesis and CLOCK gene activation
low dose naltrexone for upregulation of opiod tone and reducing any chronic inflammation state (prone to if higher body fat)
Testosterone later this year (interested in how it affects my mental state mainly)
7 8 dhf ,impossible for me to get but would synergise well with the stack imo
other ones I would want would be gb 115, neboglamine, acd 156 , tak 653, dihexa, nsi 186, prl 583
@genio
