Loomer
Banned
- Joined
- May 15, 2025
- Messages
- 371
- Reputation
- 1,289
Research on Effective Methods for Collagen Production & Skin Care:
Recommendations for Skin Care:
Dermarolling:
- 400% increase in collagen production.
- Skin becomes thicker with more than a 400% increase in collagen deposition and a significant rise in elastin. Collagen fiber bundles become thicker, more loosely woven in both papillary and reticular dermis, with a more regular lattice pattern compared to scar tissue.
Retin-A (Tretinoin):
- 80% increase in collagen formation.
- Treatment of photodamaged skin with tretinoin led to an 80% increase in collagen I formation compared to a 14% decrease with a vehicle alone. (P = 0.006).
Source: NEJM
Sunscreen:
- 56% decrease in collagen formation in photodamaged skin.
- Collagen I formation was 56% less in the papillary dermis of photodamaged skin compared to skin protected from the sun. (P<0.001).
Source: NEJM
Red Light Therapy:
- Increases collagen production (4.6 µg/ml to 36.36 µg/ml after 5 hours).
- Red light therapy is effective in boosting collagen production.
Source: PubMed
Copper Peptides:
- Enhance collagen synthesis and wound healing.
Oral Collagen Supplements:
- Promising results for skin aging and wound healing.
- Oral collagen supplements show an increase in skin elasticity, hydration, and dermal collagen density.
Source: PubMed
Source: PubMed
- Oral collagen peptides from bovine bone improve skin laxity and collagen content, though they don’t impact moisture retention.
Fasting:
- 92% decrease in collagen synthesis.
- Collagen synthesis significantly decreases in acutely fasted, vitamin C-supplemented guinea pigs.
Source: JBC
Aloe Vera:
- Stimulates collagen synthesis.
- Aloe vera (topically and orally) boosts collagen content and changes collagen composition (more type III), aiding in wound healing and scar tissue strengthening.
Source: PubMed
Source: PubMed
Vitamin C (Oral):
- Promotes collagen expression and production.
- Vitamin C is essential for collagen formation, and its use has been widely recognized in skin health.
Source: PubMed
Recommendations for Skin Care:
Cheaper option:
- Vitamin C: 500 mg/day
- Tretinoin: Work up to 0.05% (apply every day)
- Dermarolling: 1mm needles, once weekly (more effective for collagen induction)
Source: Dermaroller - Sunscreen: SPF 15 (blocks 93% of UV rays, offers the best ROI)
More expensive option:
- Vitamin C: 2g/day (drink enough water to avoid kidney stones)
- Tretinoin: Work up to 0.05% (apply every day)
- Dermarolling: 1mm needles, once weekly
- Sunscreen: SPF 50
- Bovine Collagen: 200 mg/kg of body weight
- Red Light Therapy: 15-30 minutes daily
- Aloe Vera: Topically or orally (topical seems to cause minimal irritation)