Yes you heard it right, this is not a pseudoscientific read, there is actual evidence to this.
REASON
If people had well functioning NFKB pathway, they would have maybe mild symptoms and would be assymptomatic carriers, the people who died due to covid had disrupting NFKB pathway.
NFKB PATHWAY
The NFKB pathway regulates multiple aspects of innate and adaptive immune functions and serves as a pivotal mediator of inflammatory responses. It induces many proinflammatory genes, constant activation or disruptions caused in this genes are the reason for developing autoimmune diseases. constant downregulation of this genes also causes severe problems, so its important to balance them out so that you can have a healthy functioning NFKB pathway.
If u want more info about this here are the references:
www.creative-diagnostics.com
HOW DOES IT RELATE TO COVID?
Well, the NFKB pathway is very important in fighting off diseases and viruses, and this was the main mechanism which lead to the development of covid vaccines. The vaccine introduces the Spike protein blueprint, which the immune cells recognize as a threat. The NFKB pathway quickly signals help signals which leads to the production of cytokinins, T-cells and B-cells rushing to fight against those small spike proteins present in the vaccines. Now, this vaccines indirectly strengthen ur NFKB pathways.
pmc.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov
www.frontiersin.org
SO WHAT IF I HAD A GOOD FUNCTIONING NFKB PATHWAY?
You would never experience covid then, u might have mild symptoms and be assymptomatic carriers, the people who were diagnosed with covid were often shown with dysregulated NFKB pathway.
https://www.nature.com/articles/s41440-023-01460-2
https://www.sciencedirect.com/science/article/abs/pii/S1567576921008912
https://pmc.ncbi.nlm.nih.gov/articles/PMC7525247/
all these studies argue how NFKB pathway signalling is very important for fighting off covid and that all patients diagnosed with covid always had disrupting NFKB pathway.
HOW DO I MAINTAIN A GOOD BALANCE IN MY NFKB PATHWAY
Its your diet, processed foods, lots of carbs, seed oils fuck up ur NFKB pathway, grassfed meat is one of the best, it has real antioxidants like vitamin E which ur body needs unlike plant antioxidants which are hormesis, sure that could be beneficial for low doses, but those antioxidants actually force ur body to use ur real antioxidants that is vitamin E and cholesterol, Meat also has Hyper conjugated linoleic acid which is an anti carcinogen associated with benefits and of course it has a better omega3 to 6 ratio. Environmental toxins and mitochondrial dysfunctions are also the main cause. Deuterrium is naturally present in carbs and plantsin high amounts and we know deuterium is terrible for mitochondria. another reason to eat low carb, low plant diet. Also u can detox from deuterium via sun exposure
also the other disrupters are lectins, tannins, etc.
www.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov
well all these studies show a complex relationships between these plant antinutrient and NFKB pathway, but they could disrupt the pathway depending on person to person and ofcourse their genes.
EVIDENCES SHOWING A GOOD NFKB PATHWAY LEADS TO MILD OR NO EFFECTS OF COVID VIRUS
Here are the studies:
www.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov
www.nature.com
www.news-medical.net
www.ncbi.nlm.nih.gov
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448817/; https://www.sciencedirect.com/science/article/pii/S0021925823019889
CONCLUSION
Yeah the covid 19 epidemic was not solely because of the virus, its because of our poor NFKB pathway due to poor diet and lifestyle, we would have never had covid 19 pandemic if people were healthy.
Tags:
@Spuffy @Randomized Shame @rovea @Blackpillirony
REASON
If people had well functioning NFKB pathway, they would have maybe mild symptoms and would be assymptomatic carriers, the people who died due to covid had disrupting NFKB pathway.
NFKB PATHWAY
The NFKB pathway regulates multiple aspects of innate and adaptive immune functions and serves as a pivotal mediator of inflammatory responses. It induces many proinflammatory genes, constant activation or disruptions caused in this genes are the reason for developing autoimmune diseases. constant downregulation of this genes also causes severe problems, so its important to balance them out so that you can have a healthy functioning NFKB pathway.
If u want more info about this here are the references:
The NF-kB Signaling Pathway - Creative Diagnostics
There are two major signaling pathways lead to the IK-B protein inhibitor dissociation from NF-kB dimmer and let the translocation of NF-kB dimers from the cytoplasm into the nucleus.
www.creative-diagnostics.com
HOW DOES IT RELATE TO COVID?
Well, the NFKB pathway is very important in fighting off diseases and viruses, and this was the main mechanism which lead to the development of covid vaccines. The vaccine introduces the Spike protein blueprint, which the immune cells recognize as a threat. The NFKB pathway quickly signals help signals which leads to the production of cytokinins, T-cells and B-cells rushing to fight against those small spike proteins present in the vaccines. Now, this vaccines indirectly strengthen ur NFKB pathways.
The Role of the Nuclear Factor-Kappa B (NF-κB) Pathway in SARS-CoV-2 Infection - PMC
COVID-19 is a global health threat caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is associated with a significant increase in morbidity and mortality. The present review discusses nuclear factor-kappa B (NF-κB) ...
pmc.ncbi.nlm.nih.gov
The Role of the Nuclear Factor-Kappa B (NF-κB) Pathway in SARS-CoV-2 Infection - PMC
COVID-19 is a global health threat caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is associated with a significant increase in morbidity and mortality. The present review discusses nuclear factor-kappa B (NF-κB) ...
www.ncbi.nlm.nih.gov
Frontiers | NF-κB Pathway as a Potential Target for Treatment of Critical Stage COVID-19 Patients
Patients infected with SARS-CoV-2 show a wide spectrum of clinical manifestations ranging from mild febrile illness and cough up to acute respiratory distres...
www.frontiersin.org
SO WHAT IF I HAD A GOOD FUNCTIONING NFKB PATHWAY?
You would never experience covid then, u might have mild symptoms and be assymptomatic carriers, the people who were diagnosed with covid were often shown with dysregulated NFKB pathway.
https://www.nature.com/articles/s41440-023-01460-2
https://www.sciencedirect.com/science/article/abs/pii/S1567576921008912
https://pmc.ncbi.nlm.nih.gov/articles/PMC7525247/
all these studies argue how NFKB pathway signalling is very important for fighting off covid and that all patients diagnosed with covid always had disrupting NFKB pathway.
HOW DO I MAINTAIN A GOOD BALANCE IN MY NFKB PATHWAY
Its your diet, processed foods, lots of carbs, seed oils fuck up ur NFKB pathway, grassfed meat is one of the best, it has real antioxidants like vitamin E which ur body needs unlike plant antioxidants which are hormesis, sure that could be beneficial for low doses, but those antioxidants actually force ur body to use ur real antioxidants that is vitamin E and cholesterol, Meat also has Hyper conjugated linoleic acid which is an anti carcinogen associated with benefits and of course it has a better omega3 to 6 ratio. Environmental toxins and mitochondrial dysfunctions are also the main cause. Deuterrium is naturally present in carbs and plantsin high amounts and we know deuterium is terrible for mitochondria. another reason to eat low carb, low plant diet. Also u can detox from deuterium via sun exposure
also the other disrupters are lectins, tannins, etc.
Recognition of TLR2 N-Glycans: Critical Role in ArtinM Immunomodulatory Activity - PMC
TLR2 plays a critical role in the protection against Paracoccidioides brasiliensis conferred by ArtinM administration. ArtinM, a D-mannose-binding lectin from Artocarpus heterophyllus, induces IL-12 production in macrophages and dendritic cells, ...
www.ncbi.nlm.nih.gov
Modulation of Nrf2 and NF-κB Signaling Pathways by Naturally Occurring Compounds in Relation to Cancer Prevention and Therapy. Are Combinations Better Than Single Compounds? - PMC
Nrf2 (nuclear factor erythroid 2-related factor 2) and NF-κB (nuclear factor–kappa B) signaling pathways play a central role in suppressing or inducing inflammation and angiogenesis processes. Therefore, they are involved in many steps of ...
www.ncbi.nlm.nih.gov
Recognition of TLR2 N-Glycans: Critical Role in ArtinM Immunomodulatory Activity - PMC
TLR2 plays a critical role in the protection against Paracoccidioides brasiliensis conferred by ArtinM administration. ArtinM, a D-mannose-binding lectin from Artocarpus heterophyllus, induces IL-12 production in macrophages and dendritic cells, ...
www.ncbi.nlm.nih.gov
EVIDENCES SHOWING A GOOD NFKB PATHWAY LEADS TO MILD OR NO EFFECTS OF COVID VIRUS
Here are the studies:
Severe SARS-CoV-2 disease in the context of a NF-κB2 loss-of-function pathogenic variant - PMC
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that emerged recently and has created a global pandemic. Symptomatic SARS-CoV-2 infection, termed coronavirus disease 2019 (COVID-19), has been associated with a ...
www.ncbi.nlm.nih.gov
The Role of the Nuclear Factor-Kappa B (NF-κB) Pathway in SARS-CoV-2 Infection - PMC
COVID-19 is a global health threat caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is associated with a significant increase in morbidity and mortality. The present review discusses nuclear factor-kappa B (NF-κB) ...
www.ncbi.nlm.nih.gov
The role of SARS-CoV-2-mediated NF-κB activation in COVID-19 patients - Hypertension Research
The SARS-CoV-2 pandemic, now in its third year, has had a profound impact on public health and economics all over the world. Different populations showed varied susceptibility to this virus and mortality after infection. Clinical and laboratory data revealed that the uncontrolled inflammatory...
www.nature.com
SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients
Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.
www.news-medical.net
Immune response in SARS-CoV-2 infection: the role of interferons type I and type III - PMC
There is scarce information on the human immune response to the SARS-CoV-2 infection, and on the exacerbated inflammatory reaction observed in severe COVID-19 cases. To review the available evidence on the role of interferons type I and type III to ...
www.ncbi.nlm.nih.gov
CONCLUSION
Yeah the covid 19 epidemic was not solely because of the virus, its because of our poor NFKB pathway due to poor diet and lifestyle, we would have never had covid 19 pandemic if people were healthy.
Tags:
@Spuffy @Randomized Shame @rovea @Blackpillirony
