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Info Things I use to mitigate the side effects of roids

Mandy?

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Cardiovascular and Kidney:
-Biaxol 5mg before sleeping
-telmisartan 20mg in the morning
-Aspirin 100mg
-Coenzyme Q10

Reason:My blood pressure is hypertension stage 1 without anything,with a fast resting heart rate. Usually biaxol 5mg does the job in protecting cardiovascular health and kidney health. Usually people say “the higher levels of creatinine are the reason why kidney health gets worse” while actually usually it’s the high blood pressure that just nukes the kidney. Since I already use a good beta blocker,I do low dose telmisartan instead of the usual maintence dose. Also roids,the more anabolic and androgenic they are will increase your red blood cells like crazy,that’s why you need aspirin to prevent blood from clotting. Q10 is the best thing you can get in terms of availability but alone won’t work.

Insulin sensitivity,organ health,hormonal support etc:
-N-Aceytl L-Cysteine 1800mg
-Glycine (depends)
-telmisartan (included in cardiovascular section)
-Metformin 2000mg
-Cabergoline 0.25mg 3 times a week
-Important micronutrients and minerals (magnesium,zinc etc)


Reason:Lots of roids are hepatoxic meaning they nuke your liver mostly by the enzymes,NAC is a L-glutathione precursor,a strong antioxidant. Also glycine is also an important precursor for glutathione. Now telmisartan and Metformin is to perserve insulin sensitivity,it’s kind of embarrassing to admit but so many people of my family get type 2 diabetes and it’s mostly on my mom’s side. I use caber to reduce prolactin,to prevent heart side effects don’t try to excessively lower prolactin and you might just need p5p 200-300mg for it.

@Archelaus @BlendedBlade🧿 @Currycelloser @milkjar @dipenhydramine @foidletlexi
 
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metformin will lower IGF-1 a lot which will interfere with recovery and muscle cell hyperplasia
 
metformin will lower IGF-1 a lot which will interfere with recovery and muscle cell hyperplasia
Yes,but I’m on GH+Insulin so it shouldn’t be a problem at all. I’d rather have a slightly lower IGF-1 than type 2 diabetes.
 
Cardiovascular and Kidney:
-Biaxol 5mg before sleeping
-telmisartan 20mg in the morning
-Aspirin 100mg
-Coenzyme Q10

Reason:My blood pressure is hypertension stage 1 without anything,with a fast resting heart rate. Usually biaxol 5mg does the job in protecting cardiovascular health and kidney health. Usually people say “the higher levels of creatinine are the reason why kidney health gets worse” while actually usually it’s the high blood pressure that just nukes the kidney. Since I already use a good beta blocker,I do low dose telmisartan instead of the usual maintence dose. Also roids,the more anabolic and androgenic they are will increase your red blood cells like crazy,that’s why you need aspirin to prevent blood from clotting. Q10 is the best thing you can get in terms of availability but alone won’t work.

Insulin sensitivity,organ health,hormonal support etc:
-N-Aceytl L-Cysteine 1800mg
-Glycine (depends)
-telmisartan (included in cardiovascular section)
-Metformin 2000mg
-Cabergoline 0.25mg 3 times a week
-Important micronutrients and minerals (magnesium,zinc etc)


Reason:Lots of roids are hepatoxic meaning they nuke your liver mostly by the enzymes,NAC is a L-glutathione precursor,a strong antioxidant. Also glycine is also an important precursor for glutathione. Now telmisartan and Metformin is to perserve insulin sensitivity,it’s kind of embarrassing to admit but so many people of my family get type 2 diabetes and it’s mostly on my mom’s side. I use caber to reduce prolactin,to prevent heart side effects don’t try to excessively lower prolactin and you might just need p5p 200-300mg for it.

@Archelaus @BlendedBlade🧿 @Currycelloser @milkjar @dipenhydramine @foidletlexi
😍😍 Although I'm not on cycle i bookmarked for the future. your threads are something i look forward to
 
What about lipid profile management
 
Statins or cardarine help a lot
Cardarine to my understanding increases oxidative stress specifically with something that already increases it such as tren. My lipid profiles look good,my LDL is in safe range.
 
Cardarine to my understanding increases oxidative stress specifically with something that already increases it such as tren. My lipid profiles look good,my LDL is in safe range.
It increases fat oxidation causing more oxidative stress like DNP
 
Cardiovascular and Kidney:
-Biaxol 5mg before sleeping
-telmisartan 20mg in the morning
-Aspirin 100mg
-Coenzyme Q10

Reason:My blood pressure is hypertension stage 1 without anything,with a fast resting heart rate. Usually biaxol 5mg does the job in protecting cardiovascular health and kidney health. Usually people say “the higher levels of creatinine are the reason why kidney health gets worse” while actually usually it’s the high blood pressure that just nukes the kidney. Since I already use a good beta blocker,I do low dose telmisartan instead of the usual maintence dose. Also roids,the more anabolic and androgenic they are will increase your red blood cells like crazy,that’s why you need aspirin to prevent blood from clotting. Q10 is the best thing you can get in terms of availability but alone won’t work.

Insulin sensitivity,organ health,hormonal support etc:
-N-Aceytl L-Cysteine 1800mg
-Glycine (depends)
-telmisartan (included in cardiovascular section)
-Metformin 2000mg
-Cabergoline 0.25mg 3 times a week
-Important micronutrients and minerals (magnesium,zinc etc)


Reason:Lots of roids are hepatoxic meaning they nuke your liver mostly by the enzymes,NAC is a L-glutathione precursor,a strong antioxidant. Also glycine is also an important precursor for glutathione. Now telmisartan and Metformin is to perserve insulin sensitivity,it’s kind of embarrassing to admit but so many people of my family get type 2 diabetes and it’s mostly on my mom’s side. I use caber to reduce prolactin,to prevent heart side effects don’t try to excessively lower prolactin and you might just need p5p 200-300mg for it.

@Archelaus @BlendedBlade🧿 @Currycelloser @milkjar @dipenhydramine @foidletlexi
How were you able to get Metformin without a prescription
 
Biaxol 5mg before sleeping
Biaxol 5 mg is a sensible beta-blocker for controlling heart rate and blood pressure. However, its kidney-protective effect is limited it primarily protects the kidneys from blood pressure and RAAS suppression. Saying "Biaxol directly protects kidney health" is a bit of a generalization.

telmisartan 20mg in the morning
Telmisartan 20 mg correct with a low dose, you can protect both hypertension and kidneys. However, it cannot completely protect kidney function against steroid-induced nephrotoxicity on its own.

Aspirin 100mg
Aspirin 100 mg yes, it reduces the risk of blood clots, but aspirin alone may not be sufficient if the hematocrit is very high. Gastrointestinal risks (especially with steroid + aspirin combinations) should also be considered.

Coenzyme Q10
Coenzyme Q10 is beneficial as an antioxidant, but the claim that it "provides cardiovascular protection on its own" is exaggerated. Clinical evidence is mixed it is generally more significant in combination with statin use.


The statement ‘Biaxol and Coenzyme Q10 protect the kidneys and heart’ is not absolutely true it provides partial and context-dependent protection.


Metformin 2000mg
Metformin 2000 mg is sensible for improving insulin sensitivity, but it's more protective against genetic predisposition than steroid induced insulin resistance (IR). High doses are risky if liver and kidney function are not monitored.

NAC is a L-glutathione precursor,a strong antioxidant. Also glycine is also an important precursor for glutathione.
It's true that NAC + Glycine supports glutathione. But it's wrong to say "every steroid prevents hepatotoxicity" NAC alone does not completely prevent hepatotoxicity from high-dose AAS or oral C17-AA.

Important micronutrients and minerals (magnesium,zinc etc)
Micronutrients (Zn, Mg) are important but their effect is limited they do not completely prevent steroid side effects.

I use caber to reduce prolactin,to prevent heart side effects don’t try to excessively lower prolactin and you might just need p5p 200-300mg for it.
Cabergolin does suppress prolactin, that's true. But the part about "not lowering prolactin too much to avoid heart risk," as you wrote, is debatable low doses of cabergolin are safe for most people.


It is incorrect and exaggerated to say that NAC and glycine "prevent all steroid hepatotoxicity." It is risky to claim that Metformin 2g is "safe and effective for everyone".


The general logic and connections:
that "high creatinine = poor kidney health" are correct, but creatinine is only an indicator of GFR, not a sole indicator of organ damage.

“Low-dose telmisartan with a beta-blocker” sounds logical, but the risk of hypotension or bradycardia with this combination should be considered.

“Steroids drastically increase red blood cells, aspirin is essential” that's true, but the dosage and additional precautions should be evaluated according to the high hematocrit and the risk of thrombosis. A single aspirin may not be enough.
 

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