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What you should consider when debating if you should use MT-1 (afamelanotide) or MT-2 (melanotan-II).

Ltnlifter

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What is MT-1 and MT-2?

in general the melanotan peptides function by binding to the melanocortin receptors
to increase melanin production, therefore leading to darker more tanned skin.

Why choose MT-1 over MT-2?

The difference between MT-1 and MT-2 is that MT-1 is more selective with the melanocortin
receptors it binds with (mainly MC1R). On the other hand MT-2 is less selective more
commonly binding with melanocortin receptors not located on the skin, binding with
the melanocortin receptors located on almost every part of the body. This in turn leads
to negative side effects including: cardiovascular issues, neurological effects,
renal infractions (blood flow to the kidney being blocked), rhabdomyolysis (breakdown
of muscle tissue, which can lead to kidney damage), and priapism (random painful erections).


Why you might choose MT-2 over MT-1

MT-2 works quicker, has a longer half-life, and is more cost effective. If you are on a budget and
can handle the negative side effects associated with MT-2 then MT-2 might be the choice you make
and maybe you want the random erections for some reason I don't know.


Summary:

MT-1 is considered safer than MT-2 because it has little to no negative side effects compared to MT-2's
copious amounts of side effects. In a perfect world where money isn't an issue and time is infinite MT-1
would be your best bet. Yes it takes longer and yes its more expensive but its safer and usually looks
more natural. If you do decide to pin MT-2 be wary of the negative effects and if they start to get severe
stop using it immediately.
 
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